Process of producing beta-methyltetramethylene-diamin.



UNITED STATES PATENT OFFICE.

FRITZ HOEMANN AND CARL FARBENFABRIKEN VORM. CORPORATION OF GERMANY.

COUTELLE,

FRIEDR. BAYER & C

013 ELBERFELD, GERMANY, ASSIGNORS TO 0., OF ELBERIEELD, GERMANY, A

PROCESS OF PRODUCING BETA-METHYLTETRAMETHYLENE-DIAMIN.

No Drawing,

Specification of Letters Patent.

Patented May 9, 1 911.

. To all whom it may camera:

Be it known that-we, FRITZ HOFMANN and CARL ComELLE, doctors of philosophy, chemists, citizens of the German Empire, residing at Elberfeld, Germany, have invented new and useful Improvements in Processes for Producing Beta-h/Iethyltetramethylene-Diamin, of which the following is a specification.

Our invention relates to a new and valuable process for producing beta-methyltetramethylene-dlamin.

which is a valuable intermediate compound for the production of pharmaceutical compounds, dyestufl's, etc.

The new process consists in treating the diamid of beta-methyladipic acid in 10 parts of hot water is added. After heating for a short time to 70-80" C. the product of the reaction is neutralized with BrH and then concentrated by evaporation. Sodium bromid separates which is filtered Application filed November 28, 1909. Serial No. 529,546.

oil. The filtrate contains part of the BrX a and the bromohydrate of the base (NHi. GH -CH-CHz-CHFN H2) from which the latter base is set freeby treating the solution with caustic soda. The free base is isolated in the form of an oil, it is dried and finally purified by distillation.

The "formation ofthe product takes probably place accordingto the following formula:

The process is carried out in an analogous manner on using instead of bronnn the equivalent amount of chlorin. In this case the product of'the reaction is neutralized with hydrochloric acid.

The process for producing beta-methyl tetramethylene-diamin, which process con- .sists in treating the diamid of beta-methyladipic acid with an aqueous solution at halogen in caustic alkaline 'lyes and isolating .the free base by treating the halogen salt with alkali, substantially as described.

set our hand in the presence of two subscribmg Witnesses.

FRITZ HOFMANN. 1 5. CARL COUTELLE. a 3.

Witnesses -O'r'ro Keno,

CHAS. J. WRIGHT.

In testimony whereof we have hereunto- (so I 

